02 agosto 2008

Effects of remifentanil on gastric tone

Remifentanil induced changes in gastric tone with both increases and decreases. The effect of remifentanil on gastric tone is probably dependent on the current state of the systems involved. Pre-operative fasting, bioavailability of drugs given orally (i.e. pre-medication), gastric retention with the associated risk of aspiration and the post-operative start of oral intake are examples of issues that are highly dependent on gastric motility. Gastric motility is often impaired during and after surgery/anesthesia as a result of many contributing factors. Opioids, given as part of the anesthesia and the post-operative analgesic regimes, play a major role in this impairment.

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