Comparison of propofol and sevoflurane anesthesia on human cellular immunity in patients undergoing total hip arthroplasty

General anesthesia and surgical stress are know to interfere with patients’ cellular immunity through several mechanisms such as hydrocortisone increase, inhibition of NK cell and changes of T lymphocyte subpopulations. In the present study, we compared the effect of propofol and sevoflurane anesthesia on human cellular immunity in patients undergoing total hip arthroplasty through investigation of blood hydrocortisone, peripheral nature killer (NK) cells and T lymphocyte subpopulations.

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Xiulai Zhang, Haiyan Zhou, Yi Wang, Gang Chen, Lingling Fang

Department of Anesthesiology, Second Affiliated Hospital, Medical College of Zhejiang University, Hangzhou, P.R. China

Fuente: Anahestesia On Line